Kinetics of Drug Degradation and the Effect of pH on Drug Stability Lab Report

Kinetics of Drug Degradation and the Effect of pH on Drug Stability - Lab Report Example This iodine level reading then indicates the amount of iodine and therefore the amount of the drug that had been degraded and subject to the reaction with the used up iodine (Yoshioka and Stella 2000, pp. 61-69; Cohen et al. 1984; Brucat n.d.; Laude 2011; Stretton 2004). The spectrophotometer was calibrated to 324 nm for wavelength, zeroed with the use of water, and set to absorbance recording. For the trial run, 250 mL capacity Flask 2 was used to hold 10 mL of the drug in aqueous solution making use of a pipette, together with 120 mL of water. 250 mL capacity Flask 1 was used to hold 10 mL of water, 50 mL of aqueous iodine solution, and 10 mL of H2SO4, 0.1 M, likewise making use of a pipette. All of Flask 1 was poured into Flask 2, and swirled, at the same time marking the start of the timer. Flask 2 contents were poured back into Flask 1. At the 30 second mark, the reading for absorbance is noted, and this reading is done for every 30 seconds up to the six minutes mark. The pH of the mixture is also noted. This is a run. The actual experiment is done in five iterations of this run, with the initial Flask 2 contents retained, while the Flask 1 acid and water levels were varied according to the table below (Yoshioka and Stella 2000, pp. 61-69; Cohe n et al. 1984; Brucat n.d.; Laude 2011; Stretton 2004): Using the data for the absorbance at different pH and time, the gradient is calculated with the use of LINEST and SLOPE to determine the rate of reaction. Both yield the same results. The derived rates of reaction are given below: The rate of decline of iodine concentrations is a function of the acidity of the solution, as can be seen in Graph 1. Where the pH is most acidic, which is experiment 5 at a pH value of 2.05, the rate of decline is fastest. This corresponds to the fastest rate of degradation for Drug X. Graph 2 is to be interpreted in the same manner. Where the slope is least negative

Working With Special Needs Students Changed My Life Essay -- Community

"Love cannot remain by itself — it has no meaning. Love has to be put into action and that action is service." - Mother Teresa Boom! A toy dashes across the room and slams against the nicely painted wall. A blood curdling scream comes racing through the room and my eyes rush towards a small little body sprawled out on the carpet. The body is tossing and turning about, kicking its arms and legs. While to some this predicament may seem unnerving, to me it is a normal night at OSEP. This past year I was giving the opportunity to volunteer at OSEP, a program for special needs children and their siblings. The OSEP program provides a safe place twice a month for special needs children along with their siblings, which allows their parents a few hours to relax and have a night out. Most parents of special needs children can not find babysitters who are willing to watch their child, so OSEP gives parents that chance to have a small break. In the OSEP program there is a variety of different children I had the privilege to come in contact with; these children range from mental retardation,...

Global Animal Health Market Report Essay

Animal health market mainly comprises of medicines, medicinal feed additives and vaccines and caters to both food producing and companion animals. Food producing animals are species for the production of animal protein that include cattle (both beef and dairy), swine, poultry, sheep and fish whereas companion animals include dogs, cats and horses. Animal pharmaceuticals account for more than half of the animal health products market followed by biologicals and medicinal feed additives. Economic development and related increases in disposable income, particularly in many emerging markets; increasing pet ownership; increasing demand for improved nutrition, particularly animal protein; increased focus on food safety and need for greater livestock production efficiency are major factors driving the animal health market. North America is the largest animal health market followed by Europe, Asia and Latin America. The animal health care industry in Europe is majorly dominated by France, Germany, Spain and the UK. Within Asia, countries like Japan, Australia, New Zealand, Singapore and South Korea are developed markets and are characterized by extremely strict regulations. Demand for animal health products is more in emerging markets like India, China, Indonesia, Thailand, Malaysia and Taiwan. Animal health products are subject to extensive and increasingly stringent regulations. The animal health sector is highly competitive with top 10 players accounting for around 80% of the total market in 2011. Major market players include Pfizer, Merck, Merial, Elanco and Bayer. The report analyzes the global animal health market, with focus on its major segments. It also analyzes some of the major regional markets, including the US, the UK, China and India. The report discusses the major drivers and issues being experienced by the animal health market worldwide. It profiles the top three players in the global animal health market, along with their business strategies. By combining SPSS Inc.’s data integration and analysis capabilities with our relevant findings, we have predicted the future growth of the industry. We employed various significant variables that have an impact on this industry and created regression models with SPSS Base to determine the future direction of the industry. Before deploying the regression model, the relationship between several independent or predictor variables and the dependent variable was analyzed using standard SPSS output, including charts, tables and tests.

To What Extent Is Of Mice and Men More Effective Than...

Steinbecks novel Of Mice and Men cannot accurately be compared in effectiveness of its themes with the movie Rainman. The importance of each theme differs in both- in Steinbecks novel, loneliness is the most dominant theme, and in Rainman the major theme is friendship. Levinson and Steinbeck both do a brilliant job at showing the major themes in both materials to the greatest of their potential, and the minor themes are somewhat overpowered because of this. One extremely clever way that Steinbeck has more effectively conveyed the theme of loneliness to the reader is by never letting the characters develop or change in Of Mice and Men. Very early in the novel we are introduced to George and Lennie as they are about to start new†¦show more content†¦This heightens the feeling of loneliness much more than Rainman does, because in Levinsons movie the minor characters also grow and show some development as the plot continues. The minor character Susanna, from Rainman, shows major changes in her mindset towards Ray by the end of the movie. Looking back in the film to when she is initially introduced to Ray, she extended her kindness towards him only as a means of keeping the peace between the two brothers, rather then through a genuine wish to make him feel welcome. As the story evolves, Susannas friendship towards Ray becomes something of her own free will rather then a forced gesture. This shows a strong development in Susannas mindset towards Ray, and because of this it does not effectively convey the theme of loneliness as powerfully as Steinbeck has in his novel. Another way Steinbeck effectively conveys the feeling of loneliness throughout his novel is by having only slight changes in the setting of the story The very beginning and the very end take place in the brush- the place George told Lennie to go if he did anything wrong. However, the rest of the book is set at the ranch, where Lennie and George work picking barley. This limited setting change gives Steinbeck a solid foundation, from which he can build upon to effectively portray